MET and liver cancer: To determine whether MET regulates liver cancer growth by disrupting immune surveillance, we constructed two xenograft models by inoculating wild-type (WT) and MET-depleted (Met-KO) H22 (Supplementary Fig. S1a) and Hepa1-6 (Supplementary Fig. S1b) murine liver cancer cell lines in severely immunodeficient NOD-Prkdcem26Cd52Il2rgem26Cd22 (NCG) mice and in immunocompetent C57BL/6 mice, respectively (Fig. 1a).