ANGPT1 and non-small cell lung carcinoma: ACE-2/Ang (1-7) axis overexpression has also been reported to inhibit cell proliferation in pancreatic cancer cell lines, BxPC3 and SW1990, reduce epithelial–mesenchymal transition (EMT) and inhibits the migration and invasion of non-small cell lung cancer (NSCLC) cells, A549 [116,117,118].