In regression analyses, after adjusting for age, sex, and number of teeth (Model 1), high CRS (III) associated significantly with the IgA levels against A. actinomycetemcomitans, P. gingivalis, P. endodontalis, and P. intermedia and the IgG levels against P. gingivalis, P. endodontalis, and P. intermedia. This evidence concerns the gene CD79A and congenital rubella syndrome.