UMOD and chronic kidney disease: Between CKD-T stage 1 and 2, the drop of s-Uromodulin showed borderline significance (p = 0.067), while s-Uromodulin was significantly lower in CKD-T stage 2 compared to CKD-T stage 3 (p < 0.05) and in CKD-T stage 3 compared to CKD-T stage 4 (p < 0.05).