KLRK1 and acute myeloid leukemia: Although it has been described that the DN T cell subset recognizes AML blasts preferentially in a TCR-independent manner that is, at least in part, mediated through NKG2D and DNAM-1 activating receptors [43], our results do not support a major role of DNAM-1 in the activation and recognition of target cells by DN T cells.