SERBP1 and glioblastoma: SERBP1 knockdown caused a dramatic impact on U251 and U343 cell viability as detected via MTS assay (Fig. 2a, Additional File 1: Fig. S2A, S3A) We also conducted a cell colony formation assay and observed in both lines that a decrease in SERBP1 expression dramatically reduced GBM cell ability to form colonies (Fig. 2b, Additional File 1: Fig. S3B).