Without STAR syndrome, the role of CDK10/CycM in ciliogenesis would probably be still unknown, especially if one considers that CDK10 was not retained among the hits of a sub-genome-scale RNAi screening that identified a number of novel modulators of ciliogenesis and cilium length [66]. This evidence concerns the gene CDK10 and Syndactyly - telecanthus - anogenital and renal malformations.