CD4 and infection: When we compared CD4 T cell subsets infected across the different participants, we found that Env-pseudoviruses containing CAP88 or CAP177 Envs showed a more robust infection of TSCM cells (range: 0.72–1.56% of total infected cells; Additional file 1: Figure S5b) compared to CAP228, CAP255 or CAP257 Envs (range 0.13–0.33% of total infected cells).