LAG3 and hepatocellular carcinoma: We found higher densities of LAG-3 and FGL1 in HCC tissues than in normal adjacent tissues (LAG3: 2.53 vs. 0.42 per mm2, P < 0.001; FGL1: 25.09 vs. 9.03 per mm2, P = 0.009; Fig. 3f, g).