LAG3 and neoplasm: We found the densities of LAG-3+cells were significant higher in positive FGL1 expression on tumor cells (FGL1 TC+) cases compared to negative FGL1 expression on tumor cells (FGL1 TC−) cases (P < 0.001), and in positive FGL1 expression on immune cells (FGL1 IC+) cases compared to negative FGL1 expression on immune cells (FGL1 IC−) cases (P < 0.001) (Fig. 2g, h).