CFB and age-related macular degeneration: In a meta-analysis, it has been shown that CFB rs4151667 (L9H) genotypes have protective effects against AMD [24] (pooled data: AA/TT OR = 0.99, AT/TT OR = 0.5 in Caucasians and AA/TT OR = 0.96, AT/TT OR = 0.68 in Asians).