Age (< 65 versus ≥ 65 years, p = 0.51), gender (p = 0.42), previous local/systemic therapy of liver metastases (p = 0.36), mutation status (GNAQ versus GNA11, p = 0.57), high tumor burden (> 10 metastases, p = 0.65), radiological aspect of metastases (mixed/hypovascular versus hypervascular, p = 0.77), and elevated baseline alkaline phosphatase (ALP) (> 115 U/L for men and > 98 U/L for women, p = 0.12) were not found to be predictors for OS. The gene discussed is GNA11; the disease is neoplasm.