Other features of AMACR deficiency include weakness and loss of limb sensations due to nerve damage (sensorimotor neuropathy) and muscle stiffness (spasticity), and difficulty with coordination of movement (ataxia) (Ferdinandusse et al., 2000a; Savolainen et al., 2004; Kanwal et al., 2018). Here, AMACR is linked to Sensorimotor neuropathy.