The elevation of CRP is associated with reduced function of the lymphangion. Inflammatory states cause negative lymphangiotropy, with a reduction in the amplitude and frequency of contraction. Injury begets swelling, and systemic inflammation begets heart failure. Diabetes II, influenza, infections, sepsis, and clotting are all inflammatory conditions and frequently coexist with heart failure. Treating inflammation in heart failure seems to be as reasonable a target as myocardial infarction. Here, CRP is linked to heart failure.