DMPK and myotonic dystrophy type 1: Dastidar et al. used CRISPR/Cas9 to excise a CTG-repeat expansion of the DMPK gene, abnormal length of which leads to sequestration of muscle blind-like (MBLN) splicing factors, and achieved correction efficiencies of up to 90% in myotonic dystrophy type-1 (DM1) iPSCs.