FCGR2A and acute disseminated encephalomyelitis: Although in vivo evidence of ADE in MERS is lacking, it has been shown that MERS-CoV infections depended on monoclonal antibody (MAb) concentration, binding affinity of MAb for the viral receptor DPP4, and tissue expressions of DPP4 and FcγR, providing a molecular basis of ADE in MERS-CoV (203).