Part of the active TB patients were characterized by up-regulation of genes involved in neutrophil degranulation, antimicrobial peptides and the extracellular matrix organization (Figure 3A cluster II and Figure 3B cluster III); other patients had a profile with a higher expression of genes of the interferon (IFN)-signaling, antigen presentation or the complement cascade (Figure 3A cluster II and Figure 3B cluster III) while others overexpressed genes from all these events. Here, IFNA1 is linked to tuberculosis.