CCR4 and neuropathic pain: We hypothesize that CCR4 is important for nociceptive processes in neuropathy; therefore, in the present paper, we investigated the dose-dependent influence of a single intrathecal (i.t.)or intraperitoneal (i.p.)administration of C021, a CCR4 antagonist, on tactile and thermal hypersensitivity in mouse model of neuropathic pain.