Kong et al identified that SRSF6 promoted the EMT and metastasis in colorectal cancer, and found that the knockdown of SRSF6 significantly increased the expression of E-cadherin as well as reduced the expression of Snail, Vimentin, Fibronectin and MMP9 in SW620 cells 53. The gene discussed is SRSF6; the disease is colorectal cancer.