Zhou X et al. showed that SRSF10 was up-regulated in colon cancer samples, and inhibition of SRSF10 could significantly inhibit the proliferation and tumorigenesis in colon cancer cells by regulating the expression of Bcl-2-associated transcription factor 1 (BCLAF1) isoform containing BCLAF1 exon5a 73. The gene discussed is SRSF10; the disease is colonic neoplasm.