In examining the biological function of exosomes from highly metastatic lung cancer cells and human advanced lung cancer, researchers found that those exosomes can increase Vimentin expression, promote EMT, invasion and migration of target cells.120 Exosomal miR-106b-3p from CRC cells was found abundant in metastatic CRC patients’ serum and correlated with poor prognosis. This evidence concerns the gene VIM and colorectal carcinoma.