In addition, recent studies demonstrate that HERV-K(HML2) and HERV-H are concurrently expressed with pluripotent transcriptional factors NANOG, OCT-4, and SOX-2 in mesenchymal stem cells [56], while HERV-W has been detected in cancer-stem like colorectal cancer cells [57]. The gene discussed is ERVW-1; the disease is cancer.