TF and central nervous system cancer: Thus, Liu et al. formulated transferrin modified graphene oxide for glioma-targeted drug delivery [22], Li et al. used functionalized nano-graphene oxide particles for targeted fluorescence imaging and photothermic therapy of glioma U251 cells [23], while Song and colleagues evaluated hyaluronic acid-decorated graphene oxide nanohybrids as carriers for targeted and pH-responsive anticancer therapy [24].