Thus, the ectopic expression properties of the zebrafish rag2 promoter in the mesenchymal cell compartments has been used to drive expression of KRASG12D or a myristoylated constitutively active form of Akt2 in order to generate transgenic models of rhabdomyosarcoma or liposarcoma, respectively [129,130]. This evidence concerns the gene RAG2 and rhabdomyosarcoma.