A combined analysis of these noncoding RNAs with two regulators of retinal endothelial dysfunction, Homebox antisense intergenic RNA (HOTAIR) and metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), was able to discriminate diabetic patients without retinopathy from healthy controls and NPDR and PDR from diabetic patients without retinopathy, suggesting that miR-20b and miR-17-3p may be used as noninvasive biomarkers for screening of DR and the early diagnosis of PDR [115]. The gene discussed is MALAT1; the disease is retinal disorder.