Other genes deleted in ESCC are LRP1B (2q22.1–22.2), TNFRSF10A (8p21.3), PDE4D (5q12.1), PTPRD (9q24.1), FHIT (3q14.2), RB1 (13q14.2), PTEN (10q23.21), PIK3R1 (5q13.1), FAT1 (4q35.2), ZNF750 (17q25.3), CUL1 (7q36.1), CUL5 (11q22.3) and VGLL4/ATG7 (3p25.2) [29,31,33,35]. The gene discussed is FAT1; the disease is esophageal squamous cell carcinoma.