Moreover, BDNF levels were significantly decreased in the hippocampus 24 h after ischemia/reperfusion in CD- and PDD-fed gerbils, and significantly lower levels (67.5% of CD-fed gerbils) of BDNF were found in the PDD-fed gerbils 24 h after ischemia (Figure 5C). Here, BDNF is linked to ischemia.