ZEB2/SNAIL2 might, in this model, equally contribute to the high metastatic propensity of melanomas as previously suggested for SNAIL2 [49] and recently demonstrated for ZEB2 in a mouse model in which ectopic ZEB2 expression facilitates the outgrowth of dormant disseminated melanoma cells and promotes the formation of successful metastases [44]. The gene discussed is SNAI2; the disease is melanoma.