Genes associated with the hair cycle and expressed significantly more in late anagen are FOXN1, HSD17B14 and MSX2 and in telogen FGF18 and MMP7. Immune response-associated genes are more strongly expressed in telogen HFs, such as HLA-DRB1 and CD74 (both encoding for MHC class II proteins). This evidence concerns the gene FGF18 and Hand-foot syndrome.