However, increased infiltration of NK and CD11b+Ly6G+(Gr-1+) cells in RaptorECKO tumors was not seen in the MMTV-PyMT-OVA model (Supplemental Figure 3D), suggesting that endothelial Raptor/mTORC1 has a diverse contribution to the TME depending on tumor type. This evidence concerns the gene ITGAM and neoplasm.