More detailed immunophenotyping of tumor leukocyte populations revealed no consistent changes in the proportion of CD19+ B cells, F4/80+ macrophages, CD11b+Ly6G+ myeloid cells, NK cells, or CD4+CD25+FoxP3+ regulatory T cells associated with loss of Raptor from tumor ECs (Supplemental Figure 3C). The gene discussed is RPTOR; the disease is neoplasm.