Because oncolytic NDV inherently can direct the lysis and ICD induction of tumor cells, we thus hypothesized that if NDV was additionally able to produce the DC chemokine MIP-3α by recombinant gene-engineering, then the intratumoral injection of the recombinant NDV (NDV-MIP3α) could directly produce MIP-3α in the tumor tissues. Here, CCL20 is linked to neoplasm.