Compared with non-virus-treated (only PBS) DCs, the cell culture supernatants from tumor cells infected with NDV-MIP3α or NDV-WT induced a markedly increased expression of CD80 and CD86, and the most powerful expressions of CD80 and CD86 were found on the DCs treated with the supernatant from the tumor cells infected with NDV-MIP3α (figure 3A and B), indicating the effective maturation of DCs by the supernatant from the tumor cells infected with NDV-MIP3α. This evidence concerns the gene CD80 and neoplasm.