ACTA1 and idiopathic pulmonary fibrosis: Furthermore, collagen VIα3 is highly expressed in both Dupuytren’s nodules and in the fibroblastic foci in idiopathic pulmonary fibrosis (IPF), with a distribution distinct from collagen I but closely aligned with α-SMA positive regions, thus emerging as a signature marker of myofibroblasts and a tractable therapeutic target for DD and potentially also other fibrotic diseases.