In infections caused by SARS-CoV or SARS-CoV-2, pronounced inflammation and increased secretion of IL-1β, IL-4, IL-10, IFN-γ, IFN-γ-induced protein 10 (IP-10) and monocyte chemoattractant protein 1 (MCP-1) were observed(4,62). The gene discussed is IFNG; the disease is infection.