Studies suggest that CgA has a widespread distribution in a variety of polypeptide hormone producing human and bovine tissues [3, 43], and certain studies imply that the sympathochromaffin system may be the major source of circulating chromogranin A only in situations of high-intensity sympathetic stimulation, such as in people with sepsis or cardiac arrest [11, 44]. The gene discussed is CGA; the disease is Sepsis.