In mice born from mothers that were fed the supplemented zinc diet however, there was no significant difference in the latency to enter the bright arena between wildtype (29.14 ± 13.75 s) and Shank3−/− (32.18 ± 12.18 s, p-value > 0.99) mice, showing a prevention of this anxiety behaviour. This evidence concerns the gene SHANK3 and Anxiety.