MetS patients consuming 3 g powdered N. sativa daily in 100 g bread for 2 months did not exhibit significant decreases in FBG.17 In the second study, fenugreek administered as a single serving of 56 g of bread containing 2.8 g fenugreek failed to significantly affect PPBG in eight diet-controlled diabetics, although a decrease in insulin secretion over 2 h versus placebo was reported.25 This evidence concerns the gene INS and diabetes mellitus.