All EGFR β3‐αC alterations were found in lung cancer patients and EGFR β3‐αC deletions were present in a very high frequency of 96.7% (1479/1530), with the most frequent deletion of amino acids glutamic acid‐leucine‐arginine‐glutamic acid‐alanine (also referred to as ΔELREA), followed by lower frequencies of ∆LREATS, P753S, and ∆LREAT. This evidence concerns the gene EGFR and lung cancer.