Next, we analyzed the correlation of plasma betaine with other traditional risk factors of CVD and diabetes and discovered inverse correlations of betaine with Glu (R = −0.17, P<0.01), HbA1c% (R = −0.18, P=0.05), DBP (R = −0.13, P=0.03), TG (R = −0.19, P<0.03) and ALT (R = −0.2, P<0.01) by Spearman correlation analysis (Table 2). This evidence concerns the gene GPT and diabetes mellitus.