Confocal microscopy revealed that both NDAT and PI3K inhibitor, LY294002 inhibited the abundance of PD-L1 protein in the established HT-29 CRC cell and three established primary cultures of CRC cells (Colo_160224, Colo_150624, and Colo_160426) (Figure 3A). Here, CD274 is linked to colorectal carcinoma.