AVP and cancer: The increased activity of ADH in cancer can probably explain our observation that in spite of the fact that ambient median concentrations of isopropanol for LC patients were more than 3-fold higher compared to these of HC (750.4 ng/L vs. 242.9 ng/L air), the difference in breath isopropanol was less than one and a half (527.7 ng/L air vs. 315.5 ng/L air) (Supplementary Figure S3).