MSH2 and lung cancer: The same study showed on 422 cases and 486 controls that rs1800734 in MLH1 was associated with increased lung cancer risk (OR = 1.40, 95% CI = 1.08–1.82, p = 0.01); the interaction between rs1800734 and rs2303425 (MSH2) revealed elevated risk for genotype GG/CC (OR = 3.08, 95% CI = 1.09–8.72, p = 0.03), which was further pronounced in females (OR = 11.56, 95% CI = 1.33–100.36, p = 0.005).