Nevertheless, our results show that the immunohistochemical features of the current hemangioma have clear similarities with the features described in dogs, in which VEGFR-3 was less expressed in benign vascular tumors (as in this case) and neoplastic cells show a positive signal for Vimentin, vWF, α-SMA and VEGFC. The gene discussed is FLT4; the disease is hemangioma.