GREM1 and Miyoshi myopathy: Further supporting a role for IL6 in the regulation of GREM1 in MM, a positive correlation between IL-6 and GREM1 mRNA expression was observed in both MGUS and MM patient BM stromal samples (MGUS; p = 0.0061, R = 0.533, and MM; p = 0.0458, R = 0.738); Figure 2G).