Pilar cyst often occurs in middle age with an obvious female preference and inheritance pattern of multiple cysts manifests as autosomal dominance.[5,6] Shimomura et al et al propose a monoallelic mutation in phospholipase C delta 1 (PLCD1) that result in formation of multiple pilar cysts.[7] Although pilar cyst is derived from follicular, several cases have indicated that pilar cyst can arise in non-hair bearing areas. This evidence concerns the gene PLCD1 and trichilemmal cyst.