Mucinous cystic neoplasms (MCNs) are mucin-producing epithelial neoplasms of the pancreas and are precursor lesions to invasive pancreatic cancer that usually do not communicate with the pancreatic ductal system.[1,2] Histologically, the MCNs have 2 distinct components: an inner epithelial layer and an ovarian-type sub-epithelial stroma.[1–3] The epithelial layer is composed of tall, columnar, mucin-producing cells. This evidence concerns the gene MUC5AC and pancreatic neoplasm.