Importantly, corroborating our findings in mice, using Oncomine (Rhodes et al., 2004) we found that microarray analysis of human breast stromal cells collected from patients with invasive breast carcinoma from the Finak gene set (Finak et al., 2008) showed significantly higher Sp7 expression in the tumor associated stroma compared to the adjacent normal breast tissue (Figure 2O). Here, SP7 is linked to neoplasm.