CAV1 and abdominal aortic aneurysm: Cav1, a scaffolding protein, is the main component of caveolae and is important in transmembrane cholesterol transportation, cholesterol accumulation, and cholesterol efflux.10 Furthermore, simvastatin treatment decreased Cav1 expression and increased eNOS (endothelial nitric oxide synthase) expression in patients who underwent abdominal aortic aneurysm repair.11 The study highlighted a potential link between statins and Cav1 and additionally suggested a possible pleiotropic benefit of statins outside of lipid reduction.