Out of the 132 early‐specific TF‐binding sites, such as motifs for Bach1/2, Maf(k), and Nfe2l2, 109 (83%) were significantly enriched in leukemias, whereas of the 115 intermediate‐ and mature‐specific TFs only 12 (10%) were significantly enriched in T‐ALLs (top 50 shown in Fig 4E). Here, TF is linked to leukemia.