Olaratumab, a PDGFRα inhibitor, delayed tumor formation in pediatric bone and soft tissue tumors in mice (Lowery et al., 2018); however, a combination of olaratumab and doxorubicin (ClinicalTrials.gov identifier: NCT02451943) failed to demonstrate clinical benefits in patients with soft tissue sarcoma (U.S.F.A.D. The gene discussed is PDGFRA; the disease is neoplasm.