NLRP3 and neurodegenerative disease: Increasing evidences indicated that the dysregulation of NLRP3 inflammasome plays a critical role in the pathogenesis of several inflammatory diseases, such as atypical dermatitis (Darakhshan and Pour, 2015), inflammatory bowel disease (Cocco et al., 2017) and neurodegenerative diseases (Heneka et al., 2013).