Tumor cells consistently release multiple immunosuppressive factors, including vascular endothelial growth factor (VEGF), TGF-β, IL-10, and PGE-2, to facilitate tumor growth and immune escape (Kusmartsev and Gabrilovich, 2006; Shurin et al., 2006; Lin and Karin, 2007). The gene discussed is TGFB1; the disease is neoplasm.