We detected cell viability with the CCK-8 assay and apoptosis by Western blotting and flow cytometry in lung cancer cells overexpressing LIMD1 and treated with cisplatin and found that the LIMD1 overexpression group had lower cell viability and higher rates of apoptosis than did the control group, suggesting that LIMD1 overexpression increases the sensitivity of lung cancer cells to cisplatin. Here, LIMD1 is linked to lung carcinoma.